Many longtime sports bettors will say that baseball is the easiest of the major sports in which to show a profit. The most common assumption on why sports gamblers don't wager on baseball is that they don't know how. There is no point spread and the odds used for baseball wagering look foreign to them. But it's actually quite easy.
The first thing prospective baseball bettors need to do is understand how the money line works. Smart bettors and professional gamblers will seldom give odds greater than -140 when betting on baseball and always look for a reason to bet the underdog. If you bet nothing but underdogs you can win less than half of your bets and still come out ahead in the long run.
Baseball Run Line
The run line is essentially a combination of the point spread and the money line rolled into one. Don't worry, once you see it in action, it's not nearly as confusing as it first sounds. The run line uses a constant spread of 1.5 runs, although on very rare occasions you may see it jump to 2.5 runs. The team that is favored on the money line will also be the favored team on the run line.
Baseball Over Under
Baseball totals are just like the totals for any other sport, in that you're betting the total number of points (runs in this case) is either over or under the bookmaker's predicted total. The one difference is that in many cases you will have to risk more than the standard -110 used in football and basketball totals when you place a baseball totals bet. On the positive side, there will be cases where you receive favorable odds, such as +120 when you place a totals bet in baseball.
Extra Innings and Also Pitchers
For wagering purposes what happens in extra innings counts, both for totals and run line bets. As a general rule, strikeout pitchers typically perform better in night games and may be solid underplays, while off-speed pitchers who don't register too many strikeouts are usually good overplays when they are pitching in the daytime.